Structure of PDB 5zup Chain D Binding Site BS01

Receptor Information
>5zup Chain D (length=63) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SHMEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQ
KEAGTPPLWKIAV
Ligand information
Receptor-Ligand Complex Structure
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PDB5zup Sequence preference and structural heterogeneity of BZ junctions.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K169 K170 N173 R174 Y177 G190 T191 P193
Binding residue
(residue number reindexed from 1)		K33 K34 N37 R38 Y41 G54 T55 P57
Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:5zup, PDBe:5zup, PDBj:5zup
PDBsum5zup
PubMed30184200
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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