Structure of PDB 5zr1 Chain D Binding Site BS01

Receptor Information
>5zr1 Chain D (length=438) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPGFGSLQRRLLQQLYGTLPTDEKIIFTYLQDCQQEIDRIIKQSIIQKES
HSVILVGPRQSYKTYLLDYELSLLQQSYKEQFITIRLNGFIHSEQTAING
IATQLEQQLQKIHTISSGSLTEVFEKILLLLDSSITKITVVFIFDEIDTF
AGPVRQTLLYNLFDMVEHSRVPVCIFGCTTKLNILEYLEKRVKSRFSQRV
IYMPQIQNLDDMVDAVRNLLTVRSEISPWVSQWNETLEKELSDPRSNLNR
HIRMNFETFRSLPTLKNSIIPLVATSKNFGSLCTAIKSCSFLDIYNKNQL
SNNLTGRLQSLSDLELAILISAARVALRAKDGSFNFNLAYAEYEKMIKAI
NSRINTIKLWLKKDVKNVWENLVQLDFFTEKSAVGLRDNATAAFYASNYQ
FQGTMIPFDLRSYQMQIILQELRRIIPKSNMYYSWTQL
Ligand information
>5zr1 Chain H (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aagggaaaataaacaatacataacaaaacatataaaaacca
Receptor-Ligand Complex Structure
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PDB5zr1 Structure of the origin recognition complex bound to DNA replication origin.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R478 Y486 Y490 F492 Q493
Binding residue
(residue number reindexed from 1)		R387 Y395 Y399 F401 Q402
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006270 DNA replication initiation
GO:0030466 silent mating-type cassette heterochromatin formation
Cellular Component
GO:0000808 origin recognition complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005656 nuclear pre-replicative complex
GO:0005664 nuclear origin of replication recognition complex
GO:0031261 DNA replication preinitiation complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5zr1, PDBe:5zr1, PDBj:5zr1
PDBsum5zr1
PubMed29973722
UniProtP54791|ORC4_YEAST Origin recognition complex subunit 4 (Gene Name=ORC4)

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