Structure of PDB 5y2z Chain D Binding Site BS01

Receptor Information
>5y2z Chain D (length=328) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFR
NYDNITGTSTVVCKPIVIETQLYVIVAQLFGGSHIYKRDSFANKFIKIQD
IEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIYKWNGNGFYSHQSL
HAWYRDTDVEYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQLFTNQ
TDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPS
RGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPR
SFTHVSINKRNFLFASSFKGNTQIYKHV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5y2z Chain D Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5y2z Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22.
Resolution2.67 Å
Binding residue
(original residue number in PDB)		D334 E336 D381 V382
Binding residue
(residue number reindexed from 1)		D111 E113 D158 V159
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5y2z, PDBe:5y2z, PDBj:5y2z
PDBsum5y2z
PubMed29670100
UniProtO95970|LGI1_HUMAN Leucine-rich glioma-inactivated protein 1 (Gene Name=LGI1)

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