Structure of PDB 5x2q Chain D Binding Site BS01

Receptor Information
>5x2q Chain D (length=451) Species: 8090 (Oryzias latipes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNWFNNISTDLFSMPGDIKLGGLFPIKEQSVSCDSLNKDGLGRALVMKYA
VEEINANSQLLPGVKLGYKIYNTCRHSAVIVRPALSFLTEKSNGTLSVEC
NYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLV
YPSFFRTVPSDIRQVDAMVQLIKKFNWNWVAVVGSEEEYGQQGVQQFSKK
AEDMGVCVAYQGLIPIYDDPKPAIQTIINNIQTTEVKVVVVFSLVSPAVS
FFEEVIKKNLTGVWIASSSWAISDKVYSLPNIDSIGTVIGFIDETETLEL
LSPFTEVLFKKIHEASPPYNPCPECWSLSPANVSLVKEESVQRTAFSVYA
AVYTVAHALHKLLECNSAACKWSSSTRLYPWKLLEVLKEFSVNISNTSLK
FDQNGNPNIGYSVIQRIWENQSLSSVGSYRSANLSINETLFKWYTNNSEK
P
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain5x2q Chain D Residue 951 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5x2q Structural basis for perception of diverse chemical substances by T1r taste receptors
Resolution2.6 Å
Binding residue
(original residue number in PDB)		S149 S150 G171 T173 Y221
Binding residue
(residue number reindexed from 1)		S117 S118 G139 T141 Y189
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5x2q, PDBe:5x2q, PDBj:5x2q
PDBsum5x2q
PubMed28534491
UniProtA0A173M094

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