Structure of PDB 5x2m Chain D Binding Site BS01

Receptor Information
>5x2m Chain D (length=422) Species: 8090 (Oryzias latipes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PNWFNNISTDLFSMPGDIKLGGLFPIKEQSVSCDSLNKDGLGRALVMKYA
VEEINANSQLLPGVKLGYKIYNTCRHSAVIVRPALSFLTEKSNGTLSVEC
NYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLV
YPSFFRTVPSDIRQVDAMVQLIKKFVVGSEEEYGQQGVQQFSKKAEDAYQ
GLIPIDPKPAIQTIINNIQTTEVKVVVVFSLVSPAVSFFEEVIWIASSSW
AISDKVYSLPSIGTVIGFIDETETLELLSPFTEVLFKKIHEASYNPCPEC
WSLSPANVSLVKEESVQRTAFSVYAAVYTVAHALHKLLECNSAACKWSSS
TRLYPWKLLEVLKEFSVNISNTSLKFDQNGNPNIGYSVIQRIWENQSLSS
VGSYRSANLSINETLFKWNSEK
Ligand information
Ligand IDGLN
InChIInChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChIKeyZDXPYRJPNDTMRX-VKHMYHEASA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(CC(=O)N)C(C(=O)O)N
OpenEye OEToolkits 1.5.0C(CC(=O)N)[C@@H](C(=O)O)N
ACDLabs 10.04O=C(N)CCC(N)C(=O)O
CACTVS 3.341N[CH](CCC(N)=O)C(O)=O
CACTVS 3.341N[C@@H](CCC(N)=O)C(O)=O
FormulaC5 H10 N2 O3
NameGLUTAMINE
ChEMBLCHEMBL930
DrugBankDB00130
ZINCZINC000001532526
PDB chain5x2m Chain D Residue 951 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5x2m Structural basis for perception of diverse chemical substances by T1r taste receptors
Resolution2.206 Å
Binding residue
(original residue number in PDB)		Q148 S149 S150 G171 T173 Y221
Binding residue
(residue number reindexed from 1)		Q116 S117 S118 G139 T141 Y183
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5x2m, PDBe:5x2m, PDBj:5x2m
PDBsum5x2m
PubMed28534491
UniProtA0A173M094

[Back to BioLiP]