Structure of PDB 5wrj Chain D Binding Site BS01

Receptor Information
>5wrj Chain D (length=275) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AYHKDMPLIFIGGVPRSGTTLMRAMLDAHPDIRCGEETRVIPRILALKQM
WSRSSKEKIRLDEAGVTDEVLDSAMQAFLLEIIVKHGEPAPYLCNKDPFA
LKSLTYLSRLFPNAKFLLMVRDGRASVHSMISRKVTIAGFDLNSYRDCLT
KWNRAIETMYNQCMEVGYKKCMLVHYEQLVLHPERWMRTLLKFLQIPWNH
SVLHHEEMIGKAGGVSLSKVERSTDQVIKPVNVGALSKWVGKIPPDVLQD
MAVIAPMLAKLGYDPYANPPNYGKP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5wrj Structural basis for the broad substrate specificity of the human tyrosylprotein sulfotransferase-1.
Resolution2.31 Å
Binding residue
(original residue number in PDB)		P78 E100 R102 R106 P161 T199 I200 A201
Binding residue
(residue number reindexed from 1)		P15 E37 R39 R43 P98 T136 I137 A138
Enzymatic activity
Enzyme Commision number 2.8.2.20: protein-tyrosine sulfotransferase.
Gene Ontology
Molecular Function
GO:0008476 protein-tyrosine sulfotransferase activity
Biological Process
GO:0006478 peptidyl-tyrosine sulfation

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Molecular Function
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Biological Process
External links
PDB RCSB:5wrj, PDBe:5wrj, PDBj:5wrj
PDBsum5wrj
PubMed28821720
UniProtO60507|TPST1_HUMAN Protein-tyrosine sulfotransferase 1 (Gene Name=TPST1)

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