Structure of PDB 5wlw Chain D Binding Site BS01

Receptor Information
>5wlw Chain D (length=128) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSVDLSTQVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVD
EKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELC
LPPVKLHCSILAEDAIKAALADYKLKQE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5wlw Chain D Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5wlw Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex.
Resolution3.317 Å
Binding residue
(original residue number in PDB)		D46 C70 H112
Binding residue
(residue number reindexed from 1)		D41 C65 H107
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0016226 iron-sulfur cluster assembly

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Molecular Function
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Biological Process
External links
PDB RCSB:5wlw, PDBe:5wlw, PDBj:5wlw
PDBsum5wlw
PubMed29097656
UniProtQ9H1K1|ISCU_HUMAN Iron-sulfur cluster assembly enzyme ISCU (Gene Name=ISCU)

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