Structure of PDB 5vzu Chain D Binding Site BS01
Receptor Information
>5vzu Chain D (length=417) Species:
9606
(Homo sapiens) [
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GRSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCRE
EYGVCENLRKLEITGVSCRDVYAKLLHRYRHILGLWQPDIGPYGGLLNVV
VDGLFIIGWMYLPPHDPHVDDPMRFKPLFRIHLMERKAATVECMYGHKGP
HHGHIQIVKKDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIFH
EHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLIKPGLFKGTYGSHG
LEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQRNF
NELSRIVLEVRERVRQEQQEGQPFVLPVGVSSRNEDYPRTCRMCFYGTGL
IAGHGFTSPERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADAP
SPQAFDEMLKNIQSLTS
Ligand information
>5vzu Chain F (length=6) Species:
9606
(Homo sapiens) [
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VRDVDI
Receptor-Ligand Complex Structure
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PDB
5vzu
Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
H265 Y309 H312 K330 D334 N336 I337 I473 A474 W500 L503
Binding residue
(residue number reindexed from 1)
H202 Y246 H249 K267 D271 N273 I274 I351 A352 W378 L381
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5vzu
,
PDBe:5vzu
,
PDBj:5vzu
PDBsum
5vzu
PubMed
29279382
UniProt
Q5XUX0
|FBX31_HUMAN F-box only protein 31 (Gene Name=FBXO31)
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