Structure of PDB 5v1d Chain D Binding Site BS01
Receptor Information
>5v1d Chain D (length=247) Species:
9913
(Bos taurus) [
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RSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEKMIIPS
LDGDLFQWDRDRESMETVPFTVESLLEDVVLVGGKSLTTYGLSAYSGKVR
YICSALGCRQWDILLLQRTQKTVRAVGPRSGNEKWNFSVGHFELRYIPSD
VEEQEAVMMDTVIKVSVADWKVMAFNKKGGHLEWEYQFSTPIASAWLVKD
GKVIPISLFDDTSIVEAARGATENSVYLGMYRGQLYLQSSVRISEKF
Ligand information
>5v1d Chain G (length=9) Species:
32630
(synthetic construct) [
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PQPWRFYAP
Receptor-Ligand Complex Structure
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PDB
5v1d
The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization
Resolution
2.799 Å
Binding residue
(original residue number in PDB)
M153 M172 A316 W318 V387 Y388 L389 G390
Binding residue
(residue number reindexed from 1)
M46 M65 A168 W170 V226 Y227 L228 G229
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5v1d
,
PDBe:5v1d
,
PDBj:5v1d
PDBsum
5v1d
PubMed
29386355
UniProt
A5D791
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