Structure of PDB 5o4e Chain D Binding Site BS01

Receptor Information
>5o4e Chain D (length=214) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHN
AKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTI
SKAKGQPREPQVYVYPPSRDELRFYQVSLTCLVKGFYPSDIAVEWESNGQ
PDIFPNGLNYKTTPPVLDSDGSFALVSKLTVPYPSWLMGTRFSCSVMHEA
LHNHYTQKHLEYQW
Ligand information
Ligand IDBMA
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-RWOPYEJCSA-N
SMILES
SoftwareSMILES
CACTVS 3.341OC[C@H]1O[C@@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-mannopyranose;
beta-D-mannose;
D-mannose;
mannose
ChEMBL
DrugBank
ZINCZINC000003830679
PDB chain5o4e Chain J Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5o4e Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		F241 F243
Binding residue
(residue number reindexed from 1)		F5 F7
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5o4e, PDBe:5o4e, PDBj:5o4e
PDBsum5o4e
PubMed28816592
UniProtP0DOX5|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

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