Structure of PDB 5njk Chain D Binding Site BS01
Receptor Information
>5njk Chain D (length=135) Species:
9606
(Homo sapiens) [
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TDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFF
GAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDG
TTRRWICHCFMAVKDTGERLSHAVGCAFAACLERK
Ligand information
>5njk Chain J (length=7) Species:
9606
(Homo sapiens) [
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AYIGPYL
Receptor-Ligand Complex Structure
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PDB
5njk
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
Resolution
3.13 Å
Binding residue
(original residue number in PDB)
R53 K113 V114 S115 F116 C117 R132 W139 S155 H156 G159 F162
Binding residue
(residue number reindexed from 1)
R27 K79 V80 S81 F82 C83 R98 W105 S121 H122 G125 F128
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5njk
,
PDBe:5njk
,
PDBj:5njk
PDBsum
5njk
PubMed
29269425
UniProt
P49757
|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)
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