Structure of PDB 5msm Chain D Binding Site BS01

Receptor Information
>5msm Chain D (length=370) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SINLHSAPEYDPSYKLIQLTPELLDIIQDPHQLRFKSLDKDKSEVVLCSH
DKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGFAKT
ESEFETRETHGELNLNSVPIYNGELDFSDKIMKRSSTKVIGTLEELLENS
PCSALEGISKWHKIGGSVKDGVLCILSQDFLFKALHVLLMSAMAESLDLQ
HLNVEDTHHAVGKDIEDEFNPYTREIIETVLNKFAVQEQNTWRLRIPFIA
QWYGIQALRKYVSGISMPIDEFLIKWKSLFPPFFPCDIDIDMLRGYHFKP
TDKTVQYIAKSTLPMDPKERFKVLFRLQSQWDLEDIKPLIEESRGMKIDS
FIMKYARRKRLGKKTVVTSR
Ligand information
>5msm Chain C (length=27) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
QTVKIWVKYNEGFSNAVRKNVTWNNLW
Receptor-Ligand Complex Structure
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PDB5msm Structural studies of RFC(C)(tf18) reveal a novel chromatin recruitment role for Dcc1.
Resolution2.29 Å
Binding residue
(original residue number in PDB)
M323 D324
Binding residue
(residue number reindexed from 1)
M315 D316
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0007064 mitotic sister chromatid cohesion
GO:0034088 maintenance of mitotic sister chromatid cohesion
GO:0034398 telomere tethering at nuclear periphery
GO:0035753 maintenance of DNA trinucleotide repeats
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0031390 Ctf18 RFC-like complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5msm, PDBe:5msm, PDBj:5msm
PDBsum5msm
PubMed28188145
UniProtP25559|DCC1_YEAST Sister chromatid cohesion protein DCC1 (Gene Name=DCC1)

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