Structure of PDB 5mok Chain D Binding Site BS01

Receptor Information
>5mok Chain D (length=202) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSAYLSRPSPFDLFIRKSPTITCLVVDLAPSTVQLTWSRASGKPVQHSTR
KEEKQRNGTLTVTSTLPVGTRDWIEGETYQCRVTHALMRSTTKTSGPRAA
PEVYAFATPEWPGSRDKRTLACLIQNFMPEDISVQWLHNEVQLPDARHST
TQPRKTKGSGFFVFSRLEVTRAEWEQKDEFICRAVHEAASPSQTVQRAVS
VN
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain5mok Chain H Residue 6 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5mok Thermal sensitivity and flexibility of the C epsilon 3 domains in immunoglobulin E.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		R342 P343 S344 D473 I474 P495
Binding residue
(residue number reindexed from 1)		R7 P8 S9 D131 I132 P153
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5mok, PDBe:5mok, PDBj:5mok
PDBsum5mok
PubMed28844738
UniProtP01854|IGHE_HUMAN Immunoglobulin heavy constant epsilon (Gene Name=IGHE)

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