Structure of PDB 5ld2 Chain D Binding Site BS01

Receptor Information
>5ld2 Chain D (length=605) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHV
CLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMI
LCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEI
NWQKVAAAVALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRL
AAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQ
RLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQL
ASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDS
LCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSG
EDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGV
AGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIA
LDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAAL
ILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLA
ALFSS
Ligand information
>5ld2 Chain X (length=51) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tttttttttttttctaatgcgagcactgctagcagtgctcgcattagatt
t
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ld2 Mechanism for nuclease regulation in RecBCD.
Resolution3.83 Å
Binding residue
(original residue number in PDB)		T205 T239 H241 R242 Q247 P248 V304 R445 N487 T537 H539 K540 V560
Binding residue
(residue number reindexed from 1)		T204 T238 H240 R241 Q246 P247 V303 R444 N486 T536 H538 K539 V559
Enzymatic activity
Enzyme Commision number 5.6.2.3: DNA 5'-3' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005524 ATP binding
GO:0008854 exodeoxyribonuclease V activity
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0017116 single-stranded DNA helicase activity
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0009338 exodeoxyribonuclease V complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ld2, PDBe:5ld2, PDBj:5ld2
PDBsum5ld2
PubMed27644322
UniProtP04993|RECD_ECOLI RecBCD enzyme subunit RecD (Gene Name=recD)

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