Structure of PDB 5kq1 Chain D Binding Site BS01
Receptor Information
>5kq1 Chain D (length=122) Species:
284812
(Schizosaccharomyces pombe 972h-) [
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MEDENILRNAVNLQVLKFHYPEIESIIDIASHVAVYQFDVGSQKWLKTSI
EGTFFLVKDQRARVGYVILNRNSPENLYLFINHPSNVHLVDRYLIHRTEN
QHVVGLWMFDPNDMSRIFNIVK
Ligand information
>5kq1 Chain C (length=22) Species:
9606
(Homo sapiens) [
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EPPSPSVLPKPPSHWVPVSFNP
Receptor-Ligand Complex Structure
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PDB
5kq1
Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
Resolution
3.002 Å
Binding residue
(original residue number in PDB)
Q37 N76 L77 H102
Binding residue
(residue number reindexed from 1)
Q37 N76 L77 H102
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0005515
protein binding
GO:0008047
enzyme activator activity
GO:0170008
mRNA phosphatase activator activity
Biological Process
GO:0000184
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290
deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000956
nuclear-transcribed mRNA catabolic process
GO:0006397
mRNA processing
GO:0043085
positive regulation of catalytic activity
GO:0110156
mRNA methylguanosine-cap decapping
Cellular Component
GO:0000932
P-body
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0010494
cytoplasmic stress granule
GO:0098745
RNA decapping complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:5kq1
,
PDBe:5kq1
,
PDBj:5kq1
PDBsum
5kq1
PubMed
27694842
UniProt
Q9P805
|DCP1_SCHPO mRNA-decapping enzyme subunit 1 (Gene Name=dcp1)
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