Structure of PDB 5kkq Chain D Binding Site BS01
Receptor Information
>5kkq Chain D (length=145) Species:
9606
(Homo sapiens) [
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PHKCPDCDMAFVTSGELVRHRRYKHTHEKPFKCSMCDYASVEVSKLKRHI
RSHTGERPFQCSLCSYASRDTYKLKRHMRTHSGEKPYECYICHARFTQSG
TMKMHILQKHTENVAKFHCPHCDTVIARKSDLGVHLRKQHSYIEQ
Ligand information
>5kkq Chain E (length=17) [
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tagcgccccctgctggc
Receptor-Ligand Complex Structure
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PDB
5kkq
Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Resolution
1.744 Å
Binding residue
(original residue number in PDB)
F351 Y392 Y407 S419 K423 K449 S450
Binding residue
(residue number reindexed from 1)
F31 Y72 Y87 S99 K103 K129 S130
Binding affinity
PDBbind-CN
: Kd=9nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5kkq
,
PDBe:5kkq
,
PDBj:5kkq
PDBsum
5kkq
PubMed
28529057
UniProt
P49711
|CTCF_HUMAN Transcriptional repressor CTCF (Gene Name=CTCF)
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