Structure of PDB 5jnb Chain D Binding Site BS01

Receptor Information
>5jnb Chain D (length=263) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSEKIWDYHNKVSQTDEMLQRKLHLRDMLYTAISPVFPLSGLYVVGSSLN
GFGNNSSDMDLCLMITNKDLDQKNDAVVVLNLILSTLQYEKFVESQKLIL
AKVPILRINFAAPFDDITVALNANNSVAIRNTHLLCYYSSYDWRVRPLVS
VVKEWAKRTSYSLVLMVIHFLQCGPTKVLPNLQQSYPNRFSNKVDVRTLN
VTMALEETLGELLIGFLDYYANEFNYDRDAISIRQGRRVERVCIEEPFTF
EAIKKAFREAHGE
Ligand information
>5jnb Chain H (length=25) Species: 6239 (Caenorhabditis elegans) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FRFDDYVEGAKRFDNLANLIRSSTP
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jnb Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity.
Resolution2.486 Å
Binding residue
(original residue number in PDB)		L571 R574 F585 L587 G589 L590 Y591 V592 L597 M612 I613 T614 N615 I677 T680 C684 Y685 S688 R694 R756 V760
Binding residue
(residue number reindexed from 1)		L23 R26 F37 L39 G41 L42 Y43 V44 L49 M64 I65 T66 N67 I129 T132 C136 Y137 S140 R146 R197 V201
Enzymatic activity
Enzyme Commision number 2.7.7.19: polynucleotide adenylyltransferase.
External links
PDB RCSB:5jnb, PDBe:5jnb, PDBj:5jnb
PDBsum5jnb
PubMed27288313
UniProtO17087|GLD2_CAEEL Poly(A) RNA polymerase gld-2 (Gene Name=gld-2)

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