Structure of PDB 5jm6 Chain D Binding Site BS01

Receptor Information
>5jm6 Chain D (length=445) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPEHFTQPYLDFMTHNPTVFHVVDYCKQKLLKAGYVELPARDSWTGKLVP
GGKYFTTRNGSSIIAFTVGQAYKPGNGIAMIAGHIDALTARLKPTSVKPT
KEGYVQLGVAQYAGALNETWWDRDLSVGGRVIVKDPKTGKTTVKLVKVDW
PVARIPTLAPHFGIGMTGHGNRETEMVPVIGIDNSDLPVGKPGSFASTQP
PKLVKLILSQLGLSDPDSILNWELELFDAQPATVGGLDKEFIFAGRIDDK
LCSWAAFMALLHAKRAPTDGVIKLVALFDDEEIGSLLRQGARGNFLPITI
ERILESFCSSNSVPFGPGILGQTYARSFLVSSDVTHAAHPNFTQTNLPGH
SPRLNVGVALCVDTTDSVSMAILDRIAELSGCVNQRHMIGPMLSAAMGVK
AADVGIPQLSMHSIRAMTGSLDPGLGVKFYKGFLDFWEEVDLEWS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5jm6 Chain D Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5jm6 Higher-order assemblies of oligomeric cargo receptor complexes form the membrane scaffold of the Cvt vesicle.
Resolution2.758 Å
Binding residue
(original residue number in PDB)		D306 E340 H485
Binding residue
(residue number reindexed from 1)		D248 E282 H412
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0000324 fungal-type vacuole

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jm6, PDBe:5jm6, PDBj:5jm6
PDBsum5jm6
PubMed27266708
UniProtG0SG74

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