Structure of PDB 5jjl Chain D Binding Site BS01

Receptor Information

>5jjl Chain D (length=406) Species: 83334 (Escherichia coli O157:H7)

MNLTELKNTPVSELITLGENMGRKQDIIFAILKQHAKSGEDIFGDGVLEI
LQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPERY
FALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLID
ERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDV
IILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEG
GSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDY
NRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTND
DFFEMM

Ligand information

>5jjl Chain G (length=9)

uuuuuuuuu

.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5jjl Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
• Resolution: 3.2 Å
• Binding residue (original residue number in PDB): V284 L285 G287 G288
• Binding residue (residue number reindexed from 1): V274 L275 G277 G278

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0004386 helicase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008186 ATP-dependent activity, acting on RNA
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding

Biological Process

• GO:0006353 DNA-templated transcription termination

Cellular Component

• GO:0005829 cytosol
• GO:0016020 membrane

External links

• PDB: RCSB:5jjl, PDBe:5jjl, PDBj:5jjl
• PDBsum: 5jjl
• PubMed: 27856760
• UniProt: P0AG30|RHO_ECOLI Transcription termination factor Rho (Gene Name=rho)