Structure of PDB 5jjk Chain D Binding Site BS01

Receptor Information

>5jjk Chain D (length=405) Species: 83334 (Escherichia coli O157:H7)

MNLTELKNTPVSELITLGENMGKQDIIFAILKQHAKSGEDIFGDGVLEIL
QDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPERYF
ALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTARV
LDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDE
RPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVI
ILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGG
SLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYN
RSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTNDD
FFEMM

Ligand information

>5jjk Chain G (length=7)

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Receptor-Ligand Complex Structure

Structure summary

• PDB: 5jjk Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
• Resolution: 3.15 Å
• Binding residue (original residue number in PDB): V284 L285 G287
• Binding residue (residue number reindexed from 1): V273 L274 G276

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0004386 helicase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008186 ATP-dependent activity, acting on RNA
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding

Biological Process

• GO:0006353 DNA-templated transcription termination

Cellular Component

• GO:0005829 cytosol
• GO:0016020 membrane

External links

• PDB: RCSB:5jjk, PDBe:5jjk, PDBj:5jjk
• PDBsum: 5jjk
• PubMed: 27856760
• UniProt: P0AG30|RHO_ECOLI Transcription termination factor Rho (Gene Name=rho)