Structure of PDB 5jg6 Chain D Binding Site BS01

Receptor Information
>5jg6 Chain D (length=66) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLHAQQ
VQQHCPMCRQEWKFKE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5jg6 Chain D Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5jg6 Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Resolution2.0013 Å
Binding residue
(original residue number in PDB)		C23 C26 H56 C59
Binding residue
(residue number reindexed from 1)		C5 C8 H38 C41
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
GO:0097602 cullin family protein binding
Biological Process
GO:0031145 anaphase-promoting complex-dependent catabolic process
Cellular Component
GO:0005680 anaphase-promoting complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jg6, PDBe:5jg6, PDBj:5jg6
PDBsum5jg6
PubMed27259151
UniProtQ9NYG5|APC11_HUMAN Anaphase-promoting complex subunit 11 (Gene Name=ANAPC11)

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