Structure of PDB 5itf Chain D Binding Site BS01

Receptor Information

>5itf Chain D (length=215) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

QVQLKQSGPGLVQPSQSLSITCTVSGFSLTNYGVHWVRQSPGKGLEWLGV
IWSGGNTDYNTPFTSRLSINKDNSKSQVFFKMNSLQSNDTAIYYCARALT
YYDYEFAYWGQGTLVTVSAASTKGPSVFPLAPSGGTAALGCLVKDYFPEP
VTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVN
HKPSNTKVDKRVEPK

Ligand information

>5itf Chain F (length=12) Species: 32630 (synthetic construct) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

GQFDLSTRRLKG

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5itf Natural and non-natural amino-acid side-chain substitutions: affinity and diffraction studies of meditope-Fab complexes.
Resolution	2.51 Å
Binding residue (original residue number in PDB)	Q39 P41 I92 Q111 P173
Binding residue (residue number reindexed from 1)	Q39 P41 I92 Q111 P168

External links

PDB	RCSB:5itf, PDBe:5itf, PDBj:5itf
PDBsum	5itf
PubMed	27834791

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