Structure of PDB 5gie Chain D Binding Site BS01

Receptor Information
>5gie Chain D (length=230) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPPLSMLPHLADLVSYSIQ
KVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCG
SQDYKYDVTDVSTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR
PGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSL
NEEHSKQYRSLSFQPENSMKLTPLVLEVFG
Ligand information
Receptor-Ligand Complex Structure
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PDB5gie Regulation of the vitamin D receptor by vitamin D lactam derivatives.
Resolution2.387 Å
Binding residue
(original residue number in PDB)
K242 S252 Q255 K260 P412 E416
Binding residue
(residue number reindexed from 1)
K57 S67 Q70 K75 P223 E227
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5gie, PDBe:5gie, PDBj:5gie
PDBsum5gie
PubMed27500498
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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