Structure of PDB 5fyp Chain D Binding Site BS01

Receptor Information
>5fyp Chain D (length=295) Species: 306 (Pseudomonas sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AQESPAFIDPASWNTPFNGIAQVACHNCYEKQYANTFSSVLDSVRTLELD
FWDQRDAVSGGSPHHWFVRHNPGTLFQSGNDNNCTGGKNDLEACLNDVKN
WSDKHPGHFPITLILDKKQGWSKESSGRTPKDFDELVARVFQGKLFTPQD
LATHIGSGAGALQGNLKGKSWPTANDLQGKVLLVLNHSENQKLSQYAEAR
TSKAKVFISPVTNGQNDISGKVSGMSSQSSGYVAMNNMGKGDKSWAKQAF
AYSHIGRVWGDDEVSFAQHINQKINLSAYYRFAAQSAGGYRIRPF
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5fyp Chain D Residue 1299 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5fyp The structure of a calcium-dependent phosphoinositide-specific phospholipase C from Pseudomonas sp. 62186, the first from a Gram-negative bacterium.
Resolution1.17 Å
Binding residue
(original residue number in PDB)		N27 E48 D50 D119
Binding residue
(residue number reindexed from 1)		N27 E48 D50 D116
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008081 phosphoric diester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006629 lipid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5fyp, PDBe:5fyp, PDBj:5fyp
PDBsum5fyp
PubMed28045383
UniProtA0A1S4NYD4

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