Structure of PDB 5frq Chain D Binding Site BS01

Receptor Information
>5frq Chain D (length=357) Species: 85962 (Helicobacter pylori 26695) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKISVSKNDLENALRYLQAFLDDASSIASHIHLEVIKEKLFLKASDSDIG
LKSYIFTQSSDKEGVGTINGKKFLDIISCLKDSNIILETKDDSLAIKQNK
SSFKLPMFDADEFPEFPVIDPKVSIEVNAPFLVDAFKKIAPVIEQTSHKR
ELAGILMQFDQKHQTLSVVGTDTKRLSYTQLEKISIHSTEEDISCILPKR
ALLEILKLFYENFSFKSDGMLAVIENEMHTFFTKLIDGNYPDYQKILPKE
YISSFTLGKEEFKESIKLCSSLSSTIKLTLEKNNALFESSETAKTSVEIE
KGLDIEKAFHLGVNAKFFLEALNALGTTQFVLRCNEPSSPFLIQESKIST
LMMPITL
Ligand information
Receptor-Ligand Complex Structure
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PDB5frq Structural Insight Into Beta-Clamp and its Interaction with DNA Ligase in Helicobacter Pylori
Resolution2.9 Å
Binding residue
(original residue number in PDB)		T173 T175 L178 P243 I248 M370 P371 I372 T373
Binding residue
(residue number reindexed from 1)		T171 T173 L176 P241 I246 M353 P354 I355 T356
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0009360 DNA polymerase III complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5frq, PDBe:5frq, PDBj:5frq
PDBsum5frq
PubMed27499105
UniProtO25242|DPO3B_HELPY Beta sliding clamp (Gene Name=dnaN)

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