Structure of PDB 5fer Chain D Binding Site BS01

Receptor Information
>5fer Chain D (length=80) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQ
CRAVYQARPQLHKNTVLCNVVEQFLQADLA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5fer Chain D Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5fer Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Resolution2.34 Å
Binding residue
(original residue number in PDB)		C28 H30 C50 C53
Binding residue
(residue number reindexed from 1)		C26 H28 C48 C51
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
6.3.2.n3: ISG15--protein ligase.
External links
PDB RCSB:5fer, PDBe:5fer, PDBj:5fer
PDBsum5fer
PubMed27154206
UniProtQ14258|TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 (Gene Name=TRIM25)

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