Structure of PDB 5eyz Chain D Binding Site BS01
Receptor Information
>5eyz Chain D (length=92) Species:
9606
(Homo sapiens) [
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DNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNE
GDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRPN
Ligand information
>5eyz Chain H (length=6) Species:
32630
(synthetic construct) [
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GRETEV
Receptor-Ligand Complex Structure
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PDB
5eyz
Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
Resolution
2.09 Å
Binding residue
(original residue number in PDB)
R527 F528 G529 F530 N531 V532 K533 Q538 S545 H579 D580 V583 I586
Binding residue
(residue number reindexed from 1)
R15 F16 G17 F18 N19 V20 K21 Q26 S33 H67 D68 V71 I74
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:5eyz
,
PDBe:5eyz
,
PDBj:5eyz
PDBsum
5eyz
PubMed
27246854
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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