Structure of PDB 5eu4 Chain D Binding Site BS01
Receptor Information
>5eu4 Chain D (length=276) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>5eu4 Chain F (length=9) Species:
32630
(synthetic construct) [
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YLAPGPVTA
Receptor-Ligand Complex Structure
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PDB
5eu4
A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen.
Resolution
2.12 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 R97 Y99 T143 K146 W147 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 R97 Y99 T143 K146 W147 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5eu4
,
PDBe:5eu4
,
PDBj:5eu4
PDBsum
5eu4
PubMed
26917722
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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