Structure of PDB 5ds6 Chain D Binding Site BS01

Receptor Information
>5ds6 Chain D (length=253) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIM
LEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGARSDKLLYQAK
LALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAK
QYGVTWINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDI
ADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIE
DVL
Ligand information
Receptor-Ligand Complex Structure
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PDB5ds6 Foreign DNA capture during CRISPR-Cas adaptive immunity.
Resolution3.352 Å
Binding residue
(original residue number in PDB)		D26 V27 I28 D29 G30 S61 A63
Binding residue
(residue number reindexed from 1)		D23 V24 I25 D26 G27 S58 A60
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0005515 protein binding
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ds6, PDBe:5ds6, PDBj:5ds6
PDBsum5ds6
PubMed26503043
UniProtQ46896|CAS1_ECOLI CRISPR-associated endonuclease Cas1 (Gene Name=ygbT)

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