Structure of PDB 5c08 Chain D Binding Site BS01

Receptor Information
>5c08 Chain D (length=189) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVEQDPGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSRKGPELLMYTYS
SGNKEDGRFTAQVDKSSKYISLFIRDSQPSDSATYLCAMRGDSSYKLIFG
SGTRLLVRPDIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDSD
VYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNS
Ligand information
Receptor-Ligand Complex Structure
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PDB5c08 Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution2.332 Å
Binding residue
(original residue number in PDB)		D94 Y97
Binding residue
(residue number reindexed from 1)		D92 Y95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0042605 peptide antigen binding
Biological Process
GO:0002250 adaptive immune response
Cellular Component
GO:0005886 plasma membrane
GO:0042101 T cell receptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5c08, PDBe:5c08, PDBj:5c08
PDBsum5c08
PubMed27183389
UniProtA0A0B4J271;
P01848|TRAC_HUMAN T cell receptor alpha chain constant (Gene Name=TRAC)

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