Structure of PDB 5brm Chain D Binding Site BS01
Receptor Information
>5brm Chain D (length=144) Species:
9606
(Homo sapiens) [
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DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWKCSA
PKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHF
DSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL
Ligand information
>5brm Chain J (length=13) Species:
9606
(Homo sapiens) [
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TMKRNPSFMDYFD
Receptor-Ligand Complex Structure
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PDB
5brm
Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
Resolution
2.651 Å
Binding residue
(original residue number in PDB)
R92 Y93 E94 Y95 H96 R157 Y163 F167 M171 E176 R199 E200 E206 L207
Binding residue
(residue number reindexed from 1)
R41 Y42 E43 Y44 H45 R90 Y96 F100 M104 E109 R132 E133 E139 L140
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5brm
,
PDBe:5brm
,
PDBj:5brm
PDBsum
5brm
PubMed
26108669
UniProt
Q9H8S9
|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)
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