Structure of PDB 5bqq Chain D Binding Site BS01

Receptor Information
>5bqq Chain D (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGFFYTPGH
Ligand information
>5bqq Chain B (length=27) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
FVNQHLCGSHLVEALYLVCGERGFFYT
Receptor-Ligand Complex Structure
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PDB5bqq Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Resolution1.54 Å
Binding residue
(original residue number in PDB)
H5 G8 S9 V12 E13 Y16 G23 F24 F25 Y26
Binding residue
(residue number reindexed from 1)
H5 G8 S9 V12 E13 Y16 G23 F24 F25 Y26
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:5bqq, PDBe:5bqq, PDBj:5bqq
PDBsum5bqq
PubMed26792393
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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