Structure of PDB 4zvq Chain D Binding Site BS01

Receptor Information
>4zvq Chain D (length=93) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YKIPVEADFLFAYSTVPGYVSMRSPGRGSWFVQALCSILEEHGKDLEIMQ
ILTRVNDRVARHFESCSDDPHFHEKKQIPCVVSMLTKELYFSQ
Ligand information
Receptor-Ligand Complex Structure
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PDB4zvq Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		V530 S531 M532 R533 P535
Binding residue
(residue number reindexed from 1)		V20 S21 M22 R23 P25
Enzymatic activity
Enzyme Commision number 3.4.22.60: caspase-7.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4zvq, PDBe:4zvq, PDBj:4zvq
PDBsum4zvq
PubMed27032039
UniProtP55210|CASP7_HUMAN Caspase-7 (Gene Name=CASP7)

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