Structure of PDB 4z78 Chain D Binding Site BS01
Receptor Information
>4z78 Chain D (length=277) Species:
10090
(Mus musculus) [
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MGPHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRA
PWMEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMF
GCDVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQ
AGDAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDV
TLRCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVV
PLGKEQNYTCHVHHKGLPEPLTLRWKP
Ligand information
>4z78 Chain F (length=10) Species:
9606
(Homo sapiens) [
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LYLVCGERGF
Receptor-Ligand Complex Structure
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PDB
4z78
Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
Resolution
2.304 Å
Binding residue
(original residue number in PDB)
Y7 V9 Q63 R66 D70 W73 T80 R97 F99 Y123 T143 W147 D152 Y155 Y156 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 V10 Q64 R67 D71 W74 T81 R98 F100 Y124 T144 W148 D153 Y156 Y157 Y160 E164 W168 Y172
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4z78
,
PDBe:4z78
,
PDBj:4z78
PDBsum
4z78
PubMed
26085090
UniProt
P01902
|HA1D_MOUSE H-2 class I histocompatibility antigen, K-D alpha chain (Gene Name=H2-K1)
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