Structure of PDB 4z2d Chain D Binding Site BS01
Receptor Information
>4z2d Chain D (length=194) Species:
1313
(Streptococcus pneumoniae) [
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MKSGLEIPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQAILPI
RGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMT
DADVDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPLGEMDDHQLWETTM
DPEHRLMARVSVDDAAEADKIFDMLMGDRVEPRREFIEENAVYS
Ligand information
>4z2d Chain E (length=7) [
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gttgtat
Receptor-Ligand Complex Structure
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PDB
4z2d
Structural studies of the drug-stabilized cleavage complexes of topoisomerase IV and gyrase from Streptococcus pneumoniae
Resolution
3.38 Å
Binding residue
(original residue number in PDB)
G457 K458 D510
Binding residue
(residue number reindexed from 1)
G52 K53 D105
Enzymatic activity
Catalytic site (original residue number in PDB)
Y643
Catalytic site (residue number reindexed from 1)
Y193
Enzyme Commision number
5.6.2.2
: DNA topoisomerase (ATP-hydrolyzing).
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003918
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524
ATP binding
Biological Process
GO:0006265
DNA topological change
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Molecular Function
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Biological Process
External links
PDB
RCSB:4z2d
,
PDBe:4z2d
,
PDBj:4z2d
PDBsum
4z2d
PubMed
UniProt
P0A4M0
|GYRB_STRR6 DNA gyrase subunit B (Gene Name=gyrB)
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