Structure of PDB 4un8 Chain D Binding Site BS01

Receptor Information
>4un8 Chain D (length=191) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAP
LMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMR
EQIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLD
DHRHGVYVLNISLRDRIKFVHTILSSHLNPLPPEAAALEHH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4un8 Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
G20 D21 G22 Y25 K30 R33 T41 Q42 K43 T76 R77 R124 T150 H152 D154 H156 R157 S166 L167
Binding residue
(residue number reindexed from 1)
G16 D17 G18 Y21 K26 R29 T37 Q38 K39 T72 R73 R120 T146 H148 D150 H152 R153 S162 L163
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
Biological Process
GO:0006314 intron homing
GO:0016539 intein-mediated protein splicing

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Molecular Function

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Biological Process
External links
PDB RCSB:4un8, PDBe:4un8, PDBj:4un8
PDBsum4un8
PubMed25486305
UniProtP21505|DMO1_DESMO Homing endonuclease I-DmoI

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