Structure of PDB 4um9 Chain D Binding Site BS01
Receptor Information
>4um9 Chain D (length=455) Species:
9606
(Homo sapiens) [
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GCALGGAETCEDCLLIGPQCAWCATENERCDTPANLLAKGCQLNFIENPV
SQVEILKNKPLSVGRQKNSSDIVQIAPQSLILKLRPGGAQTLQVHVRQTE
DYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVE
KPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKN
QKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMD
SKLAGIVCPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFA
VTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEV
LGDTEGLNLSFTAICNNGTLFQHQKKCSHMKVGDTASFSVTVNIPHCERR
SRHIIIKPVGLGDALELLVSPECNCDCQKVEVNSSKCHNGNGSFQCGVCA
CPRCE
Ligand information
>4um9 Chain F (length=11) Species:
9606
(Homo sapiens) [
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HGRGDLGRLKK
Receptor-Ligand Complex Structure
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PDB
4um9
Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
G5 C6 S125 A126 Y185 A217 N218 I219 T221 E223
Binding residue
(residue number reindexed from 1)
G1 C2 S113 A114 Y173 A205 N206 I207 T209 E211
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4um9
,
PDBe:4um9
,
PDBj:4um9
PDBsum
4um9
PubMed
25383667
UniProt
P18564
|ITB6_HUMAN Integrin beta-6 (Gene Name=ITGB6)
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