Structure of PDB 4ue5 Chain D Binding Site BS01

Receptor Information
>4ue5 Chain D (length=433) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVK
QLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGK
QNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQ
NATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDS
LFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKL
DGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDI
EGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILG
MIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQP
GRIQRVARGSGVSTRDVQELLTQYTKFAQMVKK
Ligand information
>4ue5 Chain A (length=299) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccgggcgcgguggcgcgcgccuguagucccagcuacucgggaggcugag
gcaggaggaucgcuugagcccaggaguucugggcugcagugcgcuaugcc
gaucggguguccgcacuaaguucggcaucaauauggugaccucccgggag
cgggggaccaccagguugccuaaggaggggugaaccggcccaggucggaa
acggagcaggucaaaacucccgugcugaucaguagugggaucgcgccugu
gaauagccacugcacuccagccugugcaacauagcgagaccccgucucu
<<<<<<<<<<......>>>>>>>....<<<<........>>>>>>>.<<<
<<.<<....<<<<<...<<.<<<<.....<<<<.<<<<<<<.<<<<<...
...<<<<<<<<<.<<<<<...<<<<<<<<<<<.<<<<<..<<<<<<....
>>>>>>..>>>>>.>>>>........<<<<<.....<<<<....<<<...
.>>>....>>>>...>>>>>.>>>>>>>....>>>>>>>...>>>>>>>.
..>>>>>>>>>>>>.>>>>.>>>>.>>.....>>>>>...>>.>>>>>.
Receptor-Ligand Complex Structure
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PDB4ue5 Translational Arrest by a Prokaryotic Signal Recognition Particle is Mediated by RNA Interactions.
Resolution9.0 Å
Binding residue
(original residue number in PDB)
G409 S410 G411
Binding residue
(residue number reindexed from 1)
G409 S410 G411
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4ue5, PDBe:4ue5, PDBj:4ue5
PDBsum4ue5
PubMed26344568
UniProtP61010|SRP54_CANLF Signal recognition particle subunit SRP54 (Gene Name=SRP54)

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