Structure of PDB 4ud7 Chain D Binding Site BS01

Receptor Information
>4ud7 Chain D (length=96) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRL
YDAAQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQ
Ligand information
Receptor-Ligand Complex Structure
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PDB4ud7 Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		L54 G58 I61 M62 Q72 H73 V93 H96
Binding residue
(residue number reindexed from 1)		L38 G42 I45 M46 Q56 H57 V77 H80
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:4ud7, PDBe:4ud7, PDBj:4ud7
PDBsum4ud7
PubMed27532490
UniProtQ00987|MDM2_HUMAN E3 ubiquitin-protein ligase Mdm2 (Gene Name=MDM2)

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