Structure of PDB 4u1l Chain D Binding Site BS01

Receptor Information
>4u1l Chain D (length=277) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQISQRKLEA
ARVAEQLRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWTAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>4u1l Chain F (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RPQVPLRPM
Receptor-Ligand Complex Structure
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PDB4u1l A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Resolution2.06 Å
Binding residue
(original residue number in PDB)		Y7 Y59 R62 N63 I66 Y67 A69 Q70 T73 S77 N80 Y84 Y99 Y116 S143 K146 A150 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)		Y8 Y60 R63 N64 I67 Y68 A70 Q71 T74 S78 N81 Y85 Y100 Y117 S144 K147 A151 Q156 L157 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4u1l, PDBe:4u1l, PDBj:4u1l
PDBsum4u1l
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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