Structure of PDB 4tu0 Chain D Binding Site BS01
Receptor Information
>4tu0 Chain D (length=159) Species:
37124
(Chikungunya virus) [
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APSYRVKRMDIAKNDEECVVNAANPRGLPGDGVCKAVYKKWPESFKNSAT
PVGTAKTVMCGTYPVIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLG
VNSVAIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEK
KISEAIQMR
Ligand information
>4tu0 Chain F (length=3) [
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Receptor-Ligand Complex Structure
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PDB
4tu0
CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
M11 D12 I13 G34 V35 T113 G114 V115 C145 R146 D147 W150
Binding residue
(residue number reindexed from 1)
M9 D10 I11 G32 V33 T111 G112 V113 C143 R144 D145 W148
Enzymatic activity
Enzyme Commision number
2.1.1.-
2.7.7.-
2.7.7.19
: polynucleotide adenylyltransferase.
2.7.7.48
: RNA-directed RNA polymerase.
3.1.3.84
: ADP-ribose 1''-phosphate phosphatase.
3.4.22.-
3.6.1.15
: nucleoside-triphosphate phosphatase.
3.6.1.74
: mRNA 5'-phosphatase.
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:4tu0
,
PDBe:4tu0
,
PDBj:4tu0
PDBsum
4tu0
PubMed
UniProt
Q8JUX6
|POLN_CHIKS Polyprotein P1234
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