Structure of PDB 4lg2 Chain D Binding Site BS01
Receptor Information
>4lg2 Chain D (length=122) Species:
386032
(Reston ebolavirus - Reston (1989)) [
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ISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGKDNNLLDTIHAEFQASLA
DGDSPQCALIQITKRVPIFQDVPPPIIHIRSRGDIPRACQKSLRPAPPSP
KIDRGWVCLFKMQDGKTLGLKI
Ligand information
>4lg2 Chain J (length=12) [
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cuagacgucuag
............
Receptor-Ligand Complex Structure
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PDB
4lg2
Ebolavirus VP35 coats the backbone of double-stranded RNA for interferon antagonism.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
C264 I267 Q268 K271 R311
Binding residue
(residue number reindexed from 1)
C57 I60 Q61 K64 R104
Binding affinity
PDBbind-CN
: Kd=0.1uM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4lg2
,
PDBe:4lg2
,
PDBj:4lg2
PDBsum
4lg2
PubMed
23824825
UniProt
Q8JPY0
|VP35_EBORR Polymerase cofactor VP35 (Gene Name=VP35)
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