Structure of PDB 4ji8 Chain D Binding Site BS01

Receptor Information
>4ji8 Chain D (length=208) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRP
SDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRL
DNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEK
SRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQ
LVIEFYSR
Ligand information
>4ji8 Chain A (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaag
acaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcgga
cgggugaguaacgcgugggugaccuacccggaagagggggacaacccggg
gaaacucgggcuaaucccccauguggacccgccccuugggguguguccaa
agggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggug
ggguaauggcccaccaaggcgacgacggguagccggucugagaggauggc
cggccacaggggcacugagacacgggccccacuccuacgggaggcagcag
uuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuugg
aggaagaagcccuucgggguguaaacuccugaacccgggacgaaaccccc
gacgaggggacugacgguaccgggguaauagcgccggccaacuccgugcc
agcagccgcgguaauacggagggcgcgagcguuacccggauucacugggc
guaaagggcguguaggcggccuggggcgucccaugugaaagaccacggcu
caaccgugggggagcgugggauacgcucaggcuagacggugggagagggu
gguggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgc
cgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaag
cguggggagcaaaccggauuagauacccggguaguccacgcccuaaacga
ugcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagc
gcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacg
ggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaa
gaaccuuaccaggccuugacaugcuagggaacccgggugaaagccugggg
ugccccgcgaggggagcccuagcacaggugcugcauggccgucgucagcu
cgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgccg
uuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaaag
cgggaggaaggaggggacgacgucuggucagcauggcccuuacggccugg
gcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaacg
gggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacc
cgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcg
gugaauacguucccgggccuuguacacaccgcccgucacgccaugggagc
gggcucuacccgaagucgccgggagccuacgggcaggcgccgaggguagg
gcccgugacuggggcgaagucguaacaagguagcuguaccggaaggugcg
gcuggauccuuucu
......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<
<<.<<<..<<<..<<.<<<<<<<<<.......>>>>>>>>>.>>>>>...
...<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<.
.....>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>.
.<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<
<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...
>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>
>>>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<
<<......<<<<....>>>>.....>>>>....<<<<<........<<<<
.....>>>>..........>>>>>......<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<
((.....<<<<...<<<.<<<<<<.<<<<<<<<<<<......<<<<<<..
...>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<
<<<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>......
.....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<
<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>
>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<
.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>..
........<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>.
..<.<.......>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<<
<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<
<<<<...<...<<<.....>>>>.....>>>>>>>.....<<<<<....>
>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>>
...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>
>>..>>....>>>.....>>>>>>>...........<<<<<<<.......
.>>>>>>>..........>>>>>>....<<<<<<<..........>>>>>
>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<
<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>>
>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>>
>>>...........
Receptor-Ligand Complex Structure
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PDB4ji8 The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Resolution3.742 Å
Binding residue
(original residue number in PDB)
G2 R3 I5 P7 V8 C9 R10 R13 R14 K22 E24 R25 K30 R35 R36 Y38 P40 G41 Q42 H43 K46 S52 Y54 A55 L58 R59 K61 Q62 R65 E72 R73 Q74 K84 K86 G87 S113 R115 Q116 R118 Q119 R122 H123 H125 V133 D134 L135 P136 S137 Y138 K151 S208 R209
Binding residue
(residue number reindexed from 1)
G1 R2 I4 P6 V7 C8 R9 R12 R13 K21 E23 R24 K29 R34 R35 Y37 P39 G40 Q41 H42 K45 S51 Y53 A54 L57 R58 K60 Q61 R64 E71 R72 Q73 K83 K85 G86 S112 R114 Q115 R117 Q118 R121 H122 H124 V132 D133 L134 P135 S136 Y137 K150 S207 R208
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4ji8, PDBe:4ji8, PDBj:4ji8
PDBsum4ji8
PubMed24152548
UniProtP80373|RS4_THET8 Small ribosomal subunit protein uS4 (Gene Name=rpsD)

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