Structure of PDB 4j24 Chain D Binding Site BS01

Receptor Information
>4j24 Chain D (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWA
KKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLD
RDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSSRKL
AHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHL
LNMKCKNVVPVYDLLLEMLNA
Ligand information
Receptor-Ligand Complex Structure
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PDB4j24 Proline primed helix length as a modulator of the nuclear receptor-coactivator interaction
Resolution2.1 Å
Binding residue
(original residue number in PDB)		I310 K314 L324 V328 E332 D489 E493 M494
Binding residue
(residue number reindexed from 1)		I47 K51 L61 V65 E69 D213 E217 M218
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4j24, PDBe:4j24, PDBj:4j24
PDBsum4j24
PubMed23437920
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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