Structure of PDB 4itt Chain D Binding Site BS01

Receptor Information
>4itt Chain D (length=158) Species: 37319 (Pseudo-nitzschia multiseries) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEELLDLFNRQVTQEFTASQVYLSASIWFDQNDWEGMAAYMLAESAEERE
HGLGFVDFANKRNIPIELQAVPAPVSCAEWSSPEDVWQSILELEQANTRS
LLNLAEAASTCHDFAVMAFLNPFHLQQVNEEDKIGSILAKVTDENRTPGL
LRSLDVVS
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain4itt Chain D Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4itt Mechanism of ferrous iron binding and oxidation by ferritin from a pennate diatom.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Y22 E44 E48 E94 E130
Binding residue
(residue number reindexed from 1)		Y22 E44 E48 E94 E130
Annotation score5
Enzymatic activity
Enzyme Commision number 1.16.3.1: ferroxidase.
Gene Ontology
Molecular Function
GO:0008199 ferric iron binding
Biological Process
GO:0006826 iron ion transport
GO:0006879 intracellular iron ion homeostasis

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Molecular Function
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Biological Process
External links
PDB RCSB:4itt, PDBe:4itt, PDBj:4itt
PDBsum4itt
PubMed23548912
UniProtB6DMH6

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