Structure of PDB 4iho Chain D Binding Site BS01
Receptor Information
>4iho Chain D (length=272) Species:
10090
(Mus musculus) [
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GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAP
WMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSG
CDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQS
GAAEHYKAFLEGECVEWLHRYLKNGNATRTDSPKAHVTHHPRSKGEVTLR
CWALGFYPADITLTWQGEELTQDMELVETRPAGDGTFQKWASVVVPLGKE
QNYTCRVYHEGLPEPLTLRWEP
Ligand information
>4iho Chain F (length=9) [
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EGPRNQDWL
Receptor-Ligand Complex Structure
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PDB
4iho
Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 Q70 W73 V76 S77 N80 Y84 Q97 S99 T143 K146 W147 S150 A152 H155 Y156 F159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 Q70 W73 V76 S77 N80 Y84 Q97 S99 T143 K146 W147 S150 A152 H155 Y156 F159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iho
,
PDBe:4iho
,
PDBj:4iho
PDBsum
4iho
PubMed
23939911
UniProt
P01899
|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)
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