Structure of PDB 4gx1 Chain D Binding Site BS01

Receptor Information

>4gx1 Chain D (length=376) Species: 243231 (Geobacter sulfurreducens PCA)

QNLKVLLLYCAFLLVMLLAYASIFRYLMWHLEGRAYSFMAGIYWTITVMT
TLGFGDITFESDAGYLFASIVTVSGVIFLDIILPFGFVSMFLAPWIERRL
RYHPTIELPDDTRGHILIFGIDPITRTLIRKLESRNHLFVVVTDNYDQAL
HLEEQEGFKVVYGSPTDAHVLAGLRVAAARSIIANLSDPDNANLCLTVRS
LCQTPIIAVVKEPVHGELLRLAGANQVVPLTRILGRYLGIRATTDELIFI
IGHGRIGCAAAAFLDRKPVPFILIDRQESPVCNDHVVVYGDATVGQTLRQ
AGIDRASGIIVTTNDDSTNIFLTLACRHLHSHIRIVARANGEENVDQLYA
AGADFVVSNASVGANILGNLLEHKES

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 4gx1 Chain C Residue 606

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4gx1 Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): T183 N210 T214
• Binding residue (residue number reindexed from 1): T166 N193 T197
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0003674 molecular_function
• GO:0008324 monoatomic cation transmembrane transporter activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006813 potassium ion transport
• GO:0008150 biological_process
• GO:0098655 monoatomic cation transmembrane transport

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:4gx1, PDBe:4gx1, PDBj:4gx1
• PDBsum: 4gx1
• PubMed: 23240087
• UniProt: Q74FS9