Structure of PDB 4gg6 Chain D Binding Site BS01
Receptor Information
>4gg6 Chain D (length=173) Species:
9606
(Homo sapiens) [
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DSPEDFVYQFKGMCYFTNGTERVRLVTRYIYNREEYARFDSDVGVYRAVT
PLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRRVEPTVTI
SPSLLVCSVTDFYPAQIKVRWFQEETTGVVSTPLIRNGDWTFQILVMLEM
RGDVYTCHVEHPSLQNPIIVEWR
Ligand information
>4gg6 Chain I (length=13) Species:
4565
(Triticum aestivum) [
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SGEGSFQPSQENP
Receptor-Ligand Complex Structure
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PDB
4gg6
Biased T cell receptor usage directed against human leukocyte antigen DQ8-restricted gliadin peptides is associated with celiac disease.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
F11 G13 C15 T28 Y30 Y37 Y47 Y60 W61 E74 V78 N82 L85
Binding residue
(residue number reindexed from 1)
F10 G12 C14 T27 Y29 Y36 Y46 Y59 W60 E73 V77 N81 L84
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:4gg6
,
PDBe:4gg6
,
PDBj:4gg6
PDBsum
4gg6
PubMed
23063329
UniProt
P01920
|DQB1_HUMAN HLA class II histocompatibility antigen, DQ beta 1 chain (Gene Name=HLA-DQB1)
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