Structure of PDB 4f2n Chain D Binding Site BS01

Receptor Information
>4f2n Chain D (length=210) Species: 5664 (Leishmania major) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LCYHTLPHLRYPAELPTLGFNYKDGIQPVMSPRQLELHYSKHHSAYVDKL
NTLGKGYEGKTIEEIILATTGINESKVMFNQAAQHFNHSFFWKCLSPGGK
PMPKTLENAIAKQFGSVDDFMVSFQQAGVNNFGSGWTWLCVDPQTKELLI
DSTSNAGCPLTSGLRPIFTADVWEHAYYKDFENRRADYLKELWQIVDWEF
VCHMYERATK
Ligand information
Ligand IDFE2
InChIInChI=1S/Fe/q+2
InChIKeyCWYNVVGOOAEACU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Fe+2]
CACTVS 3.341[Fe++]
FormulaFe
NameFE (II) ION
ChEMBL
DrugBankDB14510
ZINC
PDB chain4f2n Chain D Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4f2n Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		H58 H108 D191 H195
Binding residue
(residue number reindexed from 1)		H38 H88 D171 H175
Annotation score1
Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals
Cellular Component
GO:0005739 mitochondrion

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Molecular Function
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Cellular Component
External links
PDB RCSB:4f2n, PDBe:4f2n, PDBj:4f2n
PDBsum4f2n
PubMed25961325
UniProtQ4QIE0

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