Structure of PDB 4eb5 Chain D Binding Site BS01

Receptor Information
>4eb5 Chain D (length=138) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YSDKVFDHFQNPRNVGKIEDADGVGTVGNPVCGDLMTIYIKVKDNRIEDI
KFQTFGCAAAIATSSMATEMAKGKTIEEALKITRDAVAEALGGLPKQKMH
CSNLAADALRRAIVDYFRKNGKIDKIKELGLEKELEKM
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain4eb5 Chain D Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4eb5 (IscS-IscU)2 complex structures provide insights into Fe2S2 biogenesis and transfer.
Resolution2.53 Å
Binding residue
(original residue number in PDB)		C33 D35 C58 A61 H101 C102
Binding residue
(residue number reindexed from 1)		C32 D34 C57 A60 H100 C101
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0008198 ferrous iron binding
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006879 intracellular iron ion homeostasis
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4eb5, PDBe:4eb5, PDBj:4eb5
PDBsum4eb5
PubMed22511353
UniProtP0DMG2|ISCU2_ARCFU Iron-sulfur cluster assembly scaffold protein IscU 2 (Gene Name=iscU2)

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